Elderly patients are especially susceptible to dose related adverse effects when taking XANAX XR. a history of depression or suicidal thoughts or behavior; Its a type of benzodiazepine that is usually prescribed to people dealing with anxiety disorders. Reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. Xanax Pfizer 2mg This type of Xanax has XANAX clearly imprinted across the surface. XANAX XR passes into your breast milk and may harm your baby. Pfizer. Swallow XANAX XR tablets whole. Inactive ingredients: cellulose, corn starch, docusate sodium View Complete Details Get Latest Price Request a quote M/S Om Shree Navajeevan Medicines Other common Xanax side effects include: Difficulty speaking Problems with coordination XANAX In geriatric patients, the recommended starting dosage of XANAX XR is 0.5 mg once daily. Pfizer Reduce the dosage by no more than 0.5 mg every three days. I purchase Xanax 1mg from usamedzone online, the product I have received is absolutely real and Original. (, Neonatal Sedation and Withdrawal Syndrome (NOWS): Use of XANAX XR during pregnancy can result in neonatal sedation and neonatal withdrawal syndrome. WebAlways consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Dosage adjustment is necessary when XANAX XR and ritonavir are initiated concomitantly or when ritonavir is added to a stable dosage of XANAX XR [see Dosage and Administration (2.5), Drug Interactions (7.1)]. WebThe use of benzodiazepines, including XANAX, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose or death. XANAX XR- alprazolamtablet, extended releasePharmacia & Upjohn Company LLC, XANAX XR is a benzodiazepine indicated for the treatment of panic disorder with or without agoraphobia, in adults. Table 2 shows the incidence of adverse reactions that occurred during 6- and 8-week placebo-controlled trials in 1% or more of patients treated with XANAX XR where the incidence in patients treated with XANAX XR was greater than the incidence in placebo-treated patients. Even taking benzodiazepines as prescribed may put patients at risk for abuse and misuse of their medication. However, upon extended exposure to ritonavir (500 mg, twice daily for 10 days), CYP3A induction offset this inhibition. A person who uses alprazolam regularly and has built up a tolerance to it, might feel euphoric or extremely mellow, but someone who is not used to the drug may become heavily sedated. WebThe use of benzodiazepines, including XANAX, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose or death. However, your second dose may be given up to 6 weeks (42 days) after the first dose, if necessary. Genocide North America 2025: United States of America (Click the graphic above to view the original archived page) COVID-19 Vaccination in the United States of America (to June 2021) 174,234,573 people WebThis product information is intended only for residents of the United States. The U.S. Reproductive Health. Carbamazepine: The oral clearance of alprazolam (given in a 0.8 mg single dose) was increased from 0.900.21 mL/min/kg to 2.130.54 mL/min/kg and the elimination T1/2 was shortened (from 17.14.9 to 7.71.7 hour) following administration of 300 mg per day carbamazepine for 10 days [see Drug Interactions (7.2)]. Xanax XR is used in the treatment of panic disorder and belongs to the drug class benzodiazepines . Keep XANAX XR in a safe place and away from children. WebXANAX XR is a benzodiazepine indicated for the treatment of panic disorder with or without agoraphobia, in adults. A person who uses alprazolam regularly and has built up a tolerance to it, might feel euphoric or extremely mellow, but someone who is not used to the drug may become heavily sedated. To reduce the risk of withdrawal reactions, use a gradual taper to discontinue XANAX XR or reduce the dosage. Xanax alprazolam tablets, USP. In these studies, patients were treated with XANAX XR in a dose range of 1 mg to 10 mg once per day. This boosts the activity of a chemical called gamma-aminobutyric acid (GABA). Abuse and misuse of benzodiazepines often (but not always) involve the use of doses greater than the maximum recommended dosage and commonly involve concomitant use of other medications, alcohol, and/or illicit substances, which is associated with an increased frequency of serious adverse outcomes, including respiratory depression, overdose, or death [see Drug Abuse and Dependence (9.2)]. WebXanax is the single most prescribed psychiatric drug in the United States; belongs to the benzodiazepines group of drugs. Is your theme custom made or did you download it from somewhere? This drug is used to manage anxiety disorders or panic disorder. See 17 for PATIENT COUNSELING INFORMATION and Medication Guide. Ava is a sensor bracelet that tracks your vital signs such as skin temperature and pulse to track your health and send real-time data to the platform. Is Pfizer Xanax 2mg Discontinued Episodes of hypomania and mania have been reported in association with the use of XANAX XR in patients with depression [see Adverse Reactions (6.1)]. To reduce the risk of withdrawal reactions, use a gradual taper to discontinue XANAX XR or reduce the dosage. Inform patients about the signs and symptoms of benzodiazepine abuse, misuse, and addiction; to seek medical help if they develop these signs and/or symptoms; and on the proper disposal of unused drug [see Warnings and Precautions (5.2), Drug Abuse and Dependence (9.2)]. Alprazolam is a 1,4 benzodiazepine. Prescribe the lowest effective dosage; avoid or minimize concomitant use of CNS depressants and other substances associated with abuse, misuse, and addiction (e.g., opioid analgesics, stimulants); and advise patients on the proper disposal of unused drug. WebThe recommended starting oral dosage of XANAX for the acute treatment of patients with GAD is 0.25 mg to 0.5 mg administered three times daily. This type of Xanax has XANAX clearly imprinted across the surface. The 2-mg dose of alprazolam in a Xanax bar is a heavy dose of the drug. DailyMed Compounds that are inhibitors or inducers of CYP3A would be expected to increase or decrease plasma alprazolam concentrations, respectively. Its a type of benzodiazepine that is usually prescribed to people dealing with anxiety disorders. Physical dependence is a state that develops as a result of physiological adaptation in response to repeated drug use, manifested by withdrawal signs and symptoms after abrupt discontinuation or a significant dose reduction of a drug. WebThe street value of Xanax varies depending on location and the dosage of the pill. WebThe street value of Xanax varies depending on location and the dosage of the pill. Buy xanax online no prescription, a brand name of alprazolam, Xanax is generally prescribed for anxiety linked with depression, generalized anxiety disorder, and panic disorder. Closely monitor patients with impaired respiratory function. (, Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death. 4 yr. ago Damn, whats up with all the downvotes? In December 2020, the United Kingdom was the first country to authorize its use on an emergency basis. Is Pfizer Xanax 2mg Discontinued In many of the spontaneous case reports of adverse behavioral effects, patients were receiving other CNS drugs concomitantly and/or were described as having underlying psychiatric conditions. Easy to order and reorder. XANAX Tablets contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds. In order to better understand the underground market for this drug, StreetRx collects data on the street price of Xanax and has found that its average black-market price is approximately $7. Advise both patients and caregivers about the risks of respiratory depression and sedation when XANAX XR is used with opioids. Alprazolam exposure was not meaningfully affected in the presence of ritonavir. Protracted withdrawal symptoms may last weeks to more than 12 months. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Alprazolam concentrations may be reduced by up to 50% in smokers compared to non-smokers. Benzodiazepines are often sought by individuals who abuse drugs and other substances, and by individuals with addictive disorders [see Warnings and Precautions (5.2)]. 2mg Xanax The mean T1/2 of alprazolam was 16.3 hours (range: 9.0 to 26.9 hours) in healthy elderly subjects compared to 11.0 hours (range: 6.3 to 15.8 hours, n=16) in healthy adult subjects. There is positive evidence of human fetal risk during pregnancy. Is Pfizer Xanax 2mg Discontinued This may be caused by decreased clearance of alprazolam in patients with alcoholic liver disease. Acute withdrawal signs and symptoms associated with benzodiazepines have included abnormal involuntary movements, anxiety, blurred vision, depersonalization, depression, derealization, dizziness, fatigue, gastrointestinal adverse reactions (e.g., nausea, vomiting, diarrhea, weight loss, decreased appetite), headache, hyperacusis, hypertension, irritability, insomnia, memory impairment, muscle pain and stiffness, panic attacks, photophobia, restlessness, tachycardia, and tremor. Drug addiction is a cluster of behavioral, cognitive, and physiological phenomena that may include a strong desire to take the drug, difficulties in controlling drug use (e.g., continuing drug use despite harmful consequences, giving a higher priority to drug use than other activities and obligations), and possible tolerance or physical dependence. Serious side effects including coma and death have happened in people who have abused or misused benzodiazepines, including XANAX XR. Both types of white Xanax pills are manufactured by Pfizer. Alprazolam exerts its effect for the treatment of panic disorder through binding to the benzodiazepine site of gamma-aminobutyric acid-A (GABAA) receptors in the brain and enhances GABA-mediated synaptic inhibition. Take XANAX XR exactly as your healthcare provider prescribed. Flumazenil is intended as an adjunct to, not as a substitute for, proper management of benzodiazepine overdose. Why its used Pill with imprint XANAX 2 is White Long Bar, Anxiety Disorders. Do not share your XANAX XR with other people. -Memory problems The following clinically significant adverse reactions are described elsewhere in the labeling: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. To reduce the risk of withdrawal reactions, use a gradual taper to discontinue XANAX XR or reduce the dosage, To reduce the risk of withdrawal reactions, use a gradual taper to discontinue XANAX XR or reduce the dosage. However, the carbamazepine dose used in this study was fairly low compared to the recommended doses (10001200 mg per day); the effect at usual carbamazepine doses is unknown. Use of XANAX XR during the later stages of pregnancy can result in sedation (respiratory depression, lethargy, hypotonia) and withdrawal symptoms (hyperreflexia, irritability, restlessness, tremors, inconsolable crying, and feeding difficulties) in the neonate. Fertility. buy the best quality steroids. The effect of this meal on Tmax depended on the timing of the meal, with a reduction in Tmax by about 1/3 for subjects eating immediately before dosing and an increase in Tmax by about 1/3 for subjects eating 1 hour or more after dosing. WebThe U.S. Manifestations of alprazolam overdosage include somnolence, confusion, impaired coordination, diminished reflexes, and coma. However, following the expiration of its patent, other manufacturers are now free to make generic versions of Xanax. Elderly and weakened patients 0.25 mg 2-3 times a day. Find out more about the street price of Klonopin (Clonazepam) Xanax (Alprazolam) Xanax is one of the most commonly abused benzodiazepines. The risks of dependence and withdrawal increase with longer treatment duration and higher daily dose. Though Xanax does have legitimate medical uses, some people abuse it or take it recreationally. WebPill with imprint X 2 is Blue, Round and has been identified as Xanax XR 2 mg. Michael Langley Do not crush, chew or break XANAX XR. The vaccine was the first COVID19 vaccine to be authorized by a stringent regulatory authority for emergency use and the first cleared for regular use. Begin with minimal doses of Xanax xr (0.25-0.5 mg / day), followed by a rise first in the evening and then in the daytime. Insomnia It is dangerous to purchase Xanax on the Internet or outside the United States. WebXANAX (alprazolam) This product information is intended only for residents of the United States. BioNTech and Pfizer have advance purchase agreements of about US$3billion to provide a licensed vaccine in the United States, the European Union, the United Kingdom, Japan, Canada, Peru, Singapore and Mexico. This drug belongs to a class of drugs called benzodiazepines. Call your healthcare provider or go to the nearest hospital emergency room right away if you get any of these serious side effects. Protracted withdrawal syndrome associated with benzodiazepines is characterized by anxiety, cognitive impairment, depression, insomnia, formication, motor symptoms (e.g., weakness, tremor, muscle twitches), paresthesia, and tinnitus that persists beyond 4 to 6 weeks after initial benzodiazepine withdrawal. Abuse and misuse of benzodiazepines commonly involve concomitant use of other medications, alcohol, and/or illicit substances, which is associated with an increased frequency of serious adverse outcomes. XANAX XR may produce physical dependence from continued therapy. These are not all the possible side effects of XANAX XR. In patients with hepatic impairment, the recommended starting dosage of XANAX XR is 0.5 mg once daily. Pfizers Xanax 2mg from glass XANAX XR is contraindicated with concomitant use of all strong CYP3A inhibitors, except ritonavir [see Contraindications (4), Warnings and Precautions (5.5), Drug Interactions (7.1)]. Alprazolam is in a class of medications called benzodiazepines. Buy high quality steroids online. Xanax Wilmington, Delaware In China, BioNTech is partnered with China-based Fosun Pharma for development, marketing, and distribution rights and the vaccine is colloquially described as the FosunBioNTech COVID19 vaccine. Pfizer The pharmacokinetics of alprazolam and two of its major active metabolites (4-hydroxyalprazolam and -hydroxyalprazolam) are linear, and concentrations are proportional up to 10 mg XANAX XR given once daily. We Are shipping a Package Via Carrier United State Postal Service & FedEx. Patients treated with flumazenil should be monitored for re-sedation, respiratory depression, and other residual benzodiazepine effects for an appropriate period after treatment. Alprazolam is in a class of medications called benzodiazepines. An interim analysis of study data showed a potential efficacy of 91.3% in preventing infection within seven days of a second dose. WebThe use of benzodiazepines, including XANAX, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose or death. A theme like yours with a few simple tweeks would really make my blog jump Also, dont stop taking this medication suddenly or decrease the dosage without talking to your doctor. (, The use of benzodiazepines, including XANAX XR, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose or death. (5.2) Abrupt discontinuation or rapid dosage reduction of XANAX after for Healthcare professionals: XANAX U.S. How it works Alprazolam produced no impairment of fertility in rats at doses up to 5 mg/kg per day, which is approximately 5 times the maximum recommended human dose of 10 mg per day based on mg/m2 body surface area. The estimated background risk of major birth defects and miscarriage for the indicated population is unknown. ( 1) DOSAGE AND ADMINISTRATION Recommended starting oral dosage is 0.5 mg to 1 mg once daily (preferably in the morning). Call your doctor for medical advice about side effects. Xanax is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia). For the most recent prescribing information, please visit www.pfizer.com. Misuse is the intentional use, for therapeutic purposes, of a drug by an individual in a way other than prescribed by a health care provider or for whom it was not prescribed. Both types of white Xanax pills are manufactured by Pfizer. Xanax is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia). Find out more about the street price of Klonopin (Clonazepam) Xanax (Alprazolam) Xanax is one of the most commonly abused benzodiazepines. (5.2) Abrupt discontinuation or rapid dosage reduction of XANAX after The most common side effects include mild to moderate pain at the injection site, fatigue, and headaches. Short-term low doses of ritonavir (4 doses of 200 mg) increased mean AUC of alprazolam by about 2.5-fold, and did not significantly affect Cmax of alprazolam. It is dangerous to purchase Xanax on the Internet or outside the United States. WebXANAX XR (ALPRAZOLAM) 2MG PFIZER $150.00 $1,900.00 XANAX XR (ALPRAZOLAM) 2MG MAIN SUBSTANCE : Alpazolam CATEGORY : Benzo MANUFACTURER : Pfizer DOSAGE : 2-4 tabs/day PACKAGE : 2mg/tab 50 tabs Choose an Option Choose an option1 BOTTLE - 50 TABS2 BOTTLES - 100 TABS4 BOTTLES - 200 TABS6 BOTTLES - 300 TABS8 Xanax If your depression gets worse or you have suicidal thoughts, call your doctor right away. An immediate-release drug is released into the bloodstream more quickly. Drugs.com Alprazolam oral tablets come in immediate-release and extended-release forms, as well as an orally disintegrating form. WebXanax is the single most prescribed psychiatric drug in the United States; belongs to the benzodiazepines group of drugs. (, Recommended total daily dosage is 3 mg to 6 mg daily. Inform patients that in some cases, patients taking benzodiazepines have developed a protracted withdrawal syndrome with withdrawal symptoms lasting weeks to more than 12 months. Psychotropic medications, anticonvulsants, antihistaminics, ethanol, and other drugs which themselves produce CNS depression. (, Use with CYP3A Inducers: Increase the risk of reduced efficacy of alprazolam. The ability of alprazolam to induce human hepatic enzyme systems has not yet been determined. Instances of irritability, hostility, and intrusive thoughts have been reported during discontinuation of alprazolam in patients with posttraumatic stress disorder. XANAX XR contains alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system-active compounds. out. This Medication Guide has been approved by the U.S. Food and Drug Administration. Analyses of the relationship between treatment outcome and gender did not suggest any differential responsiveness on the basis of gender. Xanax Reserve concomitant prescribing of these drugs, 0.5 mg: white, pentagonal shaped tablets debossed with an "X" on one side and "0.5" on the other side, 1 mg: yellow, square shaped tablets debossed with an "X" on one side and "1" on the other side, 2 mg: blue, round shaped tablets debossed with an "X" on one side and "2" on the other side, 3 mg: green, triangular shaped tablets debossed with an "X" on one side and "3" on the other side, with known hypersensitivity to alprazolam or other benzodiazepines. XANAX XR is a benzodiazepine medicine. Online Doctors for Prescription For Xanax Do not drink alcohol or take other drugs that may make you sleepy or dizzy while taking XANAX XR without first talking to your healthcare provider. Fluoxetine: Coadministration of fluoxetine with alprazolam increased the maximum plasma concentration of alprazolam by 46%, decreased clearance by 21%, increased T1/2 by 17%, and decreased measured psychomotor performance. HIGHLIGHTS OF PRESCRIBING INFORMATION safely and This drug attaches to certain benzodiazepine receptors in your brain and nervous system. Although early studies reported an increased risk of congenital malformations with diazepam and chlordiazepoxide, there was no consistent pattern noted. Missed Dose of Xanax xr Reduce XANAX XR dose when a patient is initiated with ritonavir and XANAX XR concomitantly, or when ritonavir is added to a regimen where XANAX XR is stabilized. a history of drug or alcohol addiction; or The risk of dependence is increased if you take higher doses or take this drug for a longer length of time. Isolated published reports involving small numbers of patients have suggested that patients who have borderline personality disorder, a prior history of violent or aggressive behavior, or alcohol or substance abuse may be at risk for such events. Before prescribing XANAX XR and throughout treatment, assess each patient's risk for abuse, misuse, and addiction, The continued use of benzodiazepines, including XANAX XR, may lead to clinically significant physical dependence. Limited data from published literature reports the presence of alprazolam in human breast milk. (, When tapering, decrease dosage by no more than 0.5 mg every 3 days. Please let me know where you got your design. Average Cost Of Prescription Drugs Sold XANAX XR may harm your unborn baby. XANAX Increased digoxin concentrations have been reported when alprazolam was given, especially in geriatric patients (>65 years of age). The effects of alprazolam on lactation are unknown. Inactive ingredients: cellulose, corn starch, docusate sodium View Complete Details Get Latest Price Request a quote M/S Om Shree Navajeevan Medicines WebA white Xanax bar contains 2 mg in one whole pill, but can easily be split into four different segments. Required fields are marked *. (6.1). Preston Mcelheney Adverse reactions are further categorized by body system and listed in order of decreasing frequency according to the following definitions: those occurring in at least l/l00 patients (frequent); those occurring in less than l/100 patients but at least l/1000 patients (infrequent); those occurring in fewer than l/1000 patients (rare). Angioedema has been reported, taking strong cytochrome P450 3A (CYP3A) inhibitors (e.g., ketoconazole, itraconazole), except ritonavir, Neonatal Sedation and Withdrawal Syndrome, Risks in Patients with Impaired Respiratory Function, breathing stops (which may lead to the heart stopping). Controlled trials of XANAX XR for the treatment of panic disorder included dosages in the range of 1 mg to 10 mg per day. Physician Prescribing Information and Patient Information on this page may no longer be current. If a patient develops withdrawal reactions, consider pausing the taper or increasing the dosage to the previous tapered dosage level. HIGHLIGHTS OF PRESCRIBING INFORMATION safely and Do not give XANAX XR to other people, even if they have the same symptoms that you have. Tolerance is a physiological state characterized by a reduced response to a drug after repeated administration (i.e., a higher dose of a drug is required to produce the same effect that was once obtained at a lower dose). Benzodiazepines cross the placenta and may produce respiratory depression and sedation in neonates. The recommended dosage range is 3 mg to 6 mg once daily. Should any of the above events occur, alprazolam should be discontinued. 2. Further increase in the dose (up to 0.5-0.75 mg / day) is carried out with caution for good tolerability of the drug. This drug may be used as part of a combination therapy. Set id: aa58fff3-c297-49be-838b-599c32ad9835, WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS; ABUSE, MISUSE, AND ADDICTION; and DEPENDENCE AND WITHDRAWAL REACTIONS. The mean T1/2 of alprazolam was 21.8 hours (range: 9.9 to 40.4 hours) in a group of obese subjects. (of a stimulus or mental process) below the threshold of sensation or consciousness; perceived by or affecting someones mind without their being aware of it. The efficacy of XANAX XR in the treatment of panic disorder in adults was established in two 6-week, flexible-dose, placebo-controlled studies in adult patients meeting DSM-III criteria for panic disorder. Ketoconazole and itraconazole have been shown in vivo to increase plasma alprazolam concentrations 3.98 fold and 2.70 fold, respectively. Before you take XANAX XR, tell your healthcare provider about all of your medical conditions, including if you: Tell your healthcare provider about all the medicines you take. There have also been reports of withdrawal seizures upon rapid decrease or abrupt discontinuation of Xanax [see Warning and Precautions (5.2), Drug Abuse and Dependence (9.3)]. Clinical trials began in April 2020; by November 2020, the vaccine entered PhaseIII clinical trials, with over 40,000 people participating. Use the search tool below to find Pfizer distributors of Greenstone products in the United States and Puerto Rico. WebWomen's Health. Available for Android and iOS devices. Instruct patients that discontinuation or dosage reduction of XANAX XR may require a slow taper [see Warnings and Precautions (5.3), Drug Abuse and Dependence (9.3)]. Sertraline: A single dose of alprazolam 1 mg and steady state dose of sertraline (50 to 150 mg per day) did not reveal any clinically significant changes in the pharmacokinetics of alprazolam. I never even stated that the pills are real pharmaceutical grade. The most common side effects of XANAX XR include: Keep XANAX XR and all medicines out of the reach of children. In addition, the 1 mg and 3 mg tablets contain D & C yellow No. 2 mg. 100 Tablets Rx only. XANAX Advise patients not to drive or operate heavy machinery until the effects of concomitant use with the opioid have been determined [see Warnings and Precautions (5.1), Drug Interactions (7.1)]. Drugs demonstrated to be CYP3A inhibitors on the basis of clinical studies involving alprazolam: nefazodone, fluvoxamine, and cimetidine [see Drug Interaction (7.1), Clinical Pharmacology (12.3)]. These highlights do not include all the information needed to use XANAX XR safely and effectively. XANAX Monitoring of the primary outcomes from the trials will continue until August 2021, while monitoring of the secondary outcomes will continue until January 2023. Highly recommend Pharmacy. inside, 2-3 times a day, regardless of food intake. Patients with alcoholic liver disease exhibit a longer elimination half-life (19.7 hours), compared to healthy subjects (11.4 hours). Tolerance to the therapeutic effect of XANAX XR may develop; however, little tolerance develops to the amnestic reactions and other cognitive impairments caused by benzodiazepines. The dosage of Xanax pills ranges from 0.25 milligrams to 3.5 milligrams. Other Adverse Reactions Observed During the Premarketing Evaluation of XANAX XR. The 2-mg dose of alprazolam in a Xanax bar is a heavy dose of the drug. Pfizers Xanax 2mg from glass 2. Table 3 shows the incidence of discontinuation-emergent adverse reactions that occurred during short-term, placebo-controlled trials in 5% or more of patients treated with XANAX XR where the incidence in patients treated with XANAX XR was 2 times greater than the incidence in placebo-treated patients. DOSAGE AND USE: See accompanying prescribing information. Xanax is a powerful Benzodiazepine that is often prescribed to treat generalized anxiety disorder (GAD), panic disorders, and insomnia. You can ask your pharmacist or healthcare provider for information about XANAX XR that is written for health professionals. Pfizer Prior to the administration of flumazenil, necessary measures should be instituted to secure airway, ventilation, and intravenous access. Physician Prescribing Information and Patient Information on this page may no longer be current. These symptoms may reflect the development of tolerance or a time interval between doses which is longer than the duration of clinical action of the administered dose.